The easiest way of setting up a 2-color file in an image editing program, such as Illustrator or InDesign, is to set your first color’s objects in either 100% of a color channel in CMYK mode where the three other color channels not used are set to 0%. The second color would then use 100% of a different color channel. For example, your first color’s objects may be 100% black and your second color’s objects are set to 100% cyan. If you are using this method, be sure to let us know which color channel corresponds to the ink colors you have chosen for your printing.
Our Preferred Method: If you are very comfortable with Illustrator or InDesign, you may use Pantone Swatches from the Swatch Color Libraries palette in lieu of using 100% of individual CMYK color channels. We recommend using swatches from the Pantone Solid Uncoated color book.